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Growth Optimized Aminoacyl-tRNA Synthetase Levels Prevent Maximal tRNA Charging
Aminoacyl-tRNA synthetases (aaRSs) serve a dual role in charging tRNAs. Their enzymatic activities both provide protein synthesis flux and reduce uncharged tRNA levels. Although uncharged tRNAs can negatively impact bacterial growth, substantial concentrations of tRNAs remain deacylated even under n...
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| Publicat a: | Cell Syst |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484455/ https://ncbi.nlm.nih.gov/pubmed/32726597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.07.005 |
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