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Identification of a New Allosteric Binding Site for Cocaine in Dopamine Transporter

Dopamine (DA) transporter (DAT) is a major target for psychostimulant drugs of abuse such as cocaine that competitively binds to DAT, inhibits DA reuptake, and consequently increases synaptic DA levels. In addition to the central binding site inside DAT, the available experimental evidence suggests...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Chem Inf Model
Egile Nagusiak: Xu, Liang, Chen, Liao Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484383/
https://ncbi.nlm.nih.gov/pubmed/32649824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.0c00346
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