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Dopamine transporter phosphorylation site threonine 53 is stimulated by amphetamines and regulates dopamine transport, efflux, and cocaine analog binding

The dopamine transporter (DAT) controls the spatial and temporal dynamics of dopamine neurotransmission through reuptake of extracellular transmitter and is a target for addictive compounds such as cocaine, amphetamine (AMPH), and methamphetamine (METH). Reuptake is regulated by kinase pathways and...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Challasivakanaka, Sathya, Zhen, Juan, Smith, Margaret E., Reith, Maarten E. A., Foster, James D., Vaughan, Roxanne A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704487/
https://ncbi.nlm.nih.gov/pubmed/28939767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787002
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