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Dopamine transporter phosphorylation site threonine 53 is stimulated by amphetamines and regulates dopamine transport, efflux, and cocaine analog binding

The dopamine transporter (DAT) controls the spatial and temporal dynamics of dopamine neurotransmission through reuptake of extracellular transmitter and is a target for addictive compounds such as cocaine, amphetamine (AMPH), and methamphetamine (METH). Reuptake is regulated by kinase pathways and...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Challasivakanaka, Sathya, Zhen, Juan, Smith, Margaret E., Reith, Maarten E. A., Foster, James D., Vaughan, Roxanne A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704487/
https://ncbi.nlm.nih.gov/pubmed/28939767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787002
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