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Dopamine transporter oligomerization: Impact of combining protomers with differential cocaine analog binding affinities

Previous studies point to quaternary assembly of dopamine transporters (DATs) in oligomers. However, it is not clear whether the protomers function independently in the oligomer. Is each protomer an entirely separate unit that takes up dopamine and is inhibited by drugs known to block DAT function?...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Zhen, Juan, Antonio, Tamara, Cheng, Shu-Yuan, Ali, Solav, Jones, Kymry T., Reith, Maarten E. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393779/
https://ncbi.nlm.nih.gov/pubmed/25580950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13025
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