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Cardiomyocyte Specific Deletion of p53 Decreases Cell Injury During Ischemia-Reperfusion: Role of Mitochondria
p53 is a tumor suppressor protein with a very low content in the basal condition, but the content rapidly rises during stress conditions including ischemia-reperfusion. An increase in p53 content increases cardiac injury during ischemia-reperfusion. Since mitochondrial damage plays a key role in car...
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| Udgivet i: | Free Radic Biol Med |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484321/ https://ncbi.nlm.nih.gov/pubmed/32711023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2020.06.006 |
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