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Blockade of electron transport before ischemia protects mitochondria and decreases myocardial injury during reperfusion in aged rat hearts

Myocardial injury is increased in the aged heart following ischemia and reperfusion (I-R) in both humans and experimental models. Hearts from aged 24 mo. old Fischer 344 rats sustain greater cell death and decreased contractile recovery after I-R compared to 6 mo. adult controls. Cardiac mitochondri...

詳細記述

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書誌詳細
主要な著者: Tanaka-Esposito, Christine, Chen, Qun, Lesnefsky, Edward J.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423471/
https://ncbi.nlm.nih.gov/pubmed/22698829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2012.01.024
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