Cardiac Specific Knockout of p53 Decreases ER Stress-Induced Mitochondrial Damage

Endoplasmic reticulum (ER) stress contributes to cardiovascular disease including heart failure. Interactions between the ER and mitochondria during ER stress can impair the mitochondrial respiratory chain and increase cell injury. p53 is a tumor suppressor protein that regulates apoptosis. p53 cont...

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Detalles Bibliográficos
Publicado en:Front Cardiovasc Med
Main Authors: Chen, Qun, Thompson, Jeremy, Hu, Ying, Das, Anindita, Lesnefsky, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Cardiovascular Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389610/
https://ncbi.nlm.nih.gov/pubmed/30838215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2019.00010
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