Activation of mitochondrial calpain and increased cardiac injury: beyond AIF release

Calpain 1 (CPN1) is a ubiquitous cysteine protease that exists in both cytosol and cardiac mitochondria. Mitochondrial CPN1 (mit-CPN1) is located in the intermembrane space and matrix. Activation of mit-CPN1 within the intermembrane space increases cardiac injury by releasing apoptosis-inducing fact...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Heart Circ Physiol
Prif Awduron: Thompson, Jeremy, Hu, Ying, Lesnefsky, Edward J., Chen, Qun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2015
Pynciau:
Call for Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796621/
https://ncbi.nlm.nih.gov/pubmed/26637561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00748.2015
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