Copy Number Loss of 17q22 is Associated with Enzalutamide Resistance and Poor Prognosis in Metastatic Castration-Resistant Prostate Cancer

PURPOSE: The purpose of this study was to measure genomic changes that emerge with enzalutamide treatment using analyses of whole genome sequencing and RNA sequencing. EXPERIMENTAL DESIGN: One hundred and one tumors from men with mCRPC who had not been treated with enzalutamide (n=64) or who had enz...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Clin Cancer Res
Главные авторы: Guan, Xiangnan, Sun, Duanchen, Lu, Eric, Urrutia, Joshua A., Reiter, Robert Evan, Rettig, Matthew, Evans, Christopher P., Lara, Primo, Gleave, Martin, Beer, Tomasz M., Thomas, George V., Huang, Jiaoti, Aggarwal, Rahul R., Quigley, David A., Foye, Adam, Chen, William S., Youngren, Jack, Weinstein, Alana S., Stuart, Joshua M., Feng, Felix Y., Small, Eric J., Xia, Zheng, Alumkal, Joshi J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484240/
https://ncbi.nlm.nih.gov/pubmed/32727885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-2303
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы