Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer

BACKGROUND: Metastatic castration-resistant prostate cancer (mCRPC) is the lethal form of the disease. Several recent studies have identified genomic alterations in mCRPC, but the clinical implications of these genomic alterations have not been fully elucidated. OBJECTIVE: To use whole-genome sequen...

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Udgivet i:Eur Urol
Main Authors: Chen, William S., Aggarwal, Rahul, Zhang, Li, Zhao, Shuang G., Thomas, George V., Beer, Tomasz M., Quigley, David A., Foye, Adam, Playdle, Denise, Huang, Jiaoti, Lloyd, Paul, Lu, Eric, Sun, Duanchen, Guan, Xiangnan, Rettig, Matthew, Gleave, Martin, Evans, Christopher P., Youngren, Jack, True, Lawrence, Lara, Primo, Kothari, Vishal, Xia, Zheng, Chi, Kim N., Reiter, Robert E., Maher, Christopher A., Feng, Felix Y., Small, Eric J., Alumkal, Joshi J.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764911/
https://ncbi.nlm.nih.gov/pubmed/30928160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2019.03.020
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