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The Two Amino Acids Proximate to the Renin Cleavage Site of Human Angiotensinogen Do Not Affect Blood Pressure and Atherosclerosis in Mice
OBJECTIVE: Renin cleavage of angiotensinogen (AGT) has species specificity. Since the residues at positions 11 and 12 are different between human AGT and mouse AGT, we determined whether these two residues in AGT affect renin cleavage and angiotensin II-mediated blood pressure regulation and atheros...
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| Publicat a: | Arterioscler Thromb Vasc Biol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7483780/ https://ncbi.nlm.nih.gov/pubmed/32640904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.314048 |
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