HPP1 Ectodomain Shedding is Mediated by ADAM17 and is Necessary for Tumor Suppression in Colon Cancer

BACKGROUND: Hyperplastic Polyposis Protein 1 (HPP1) encodes a tumor suppressive transmembrane cleavable Epidermal Growth Factor (EGF)-like ligand. It is unclear as to whether cleavage and shedding of HPP1 are essential steps in achieving its tumor suppressive properties. ADAM proteins are key player...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Surg Res
Autori principali: Elahi, Abul, Ajidahun, Abidemi, Hendrick, Leah, Getun, Irina, Humphries, Leigh Ann, Hernandez, Jonathan, Shibata, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483406/
https://ncbi.nlm.nih.gov/pubmed/32450419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2020.04.010
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi