A feedforward circuit shaped by ECT2 and USP7 contributes to breast carcinogenesis

Rationale: A number of guanine nucleotide exchange factors (GEFs) including epithelial cell transforming factor ECT2 are believed to drive carcinogenesis through activating distinct oncogenic GTPases. Yet, whether GEF-independent activity of ECT2 also plays a role in tumorigenesis remains unclear. M...

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Udgivet i:Theranostics
Main Authors: Zhang, Qi, Cao, Cheng, Gong, Wenchen, Bao, Kaiwen, Wang, Qian, Wang, Yuejiao, Bi, Liyuan, Ma, Shuai, Zhao, Jiao, Liu, Ling, Tian, Shanshan, Zhang, Kai, Yang, Jie, Yao, Zhi, Song, Nan, Shi, Lei
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482815/
https://ncbi.nlm.nih.gov/pubmed/32929379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.46878
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