Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis

The histone demethylase PHF8 has been implicated in multiple pathological disorders, including X-linked mental retardation and tumorigenesis. However, it is not clear how the abundance and function of PHF8 are regulated. Here, we report that PHF8 physically associates with the deubiquitinase USP7. S...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Wang, Qian, Ma, Shuai, Song, Nan, Li, Xin, Liu, Ling, Yang, Shangda, Ding, Xiang, Shan, Lin, Zhou, Xing, Su, Dongxue, Wang, Yue, Zhang, Qi, Liu, Xinhua, Yu, Na, Zhang, Kai, Shang, Yongfeng, Yao, Zhi, Shi, Lei
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887182/
https://ncbi.nlm.nih.gov/pubmed/27183383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85747
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires