Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis

The histone demethylase PHF8 has been implicated in multiple pathological disorders, including X-linked mental retardation and tumorigenesis. However, it is not clear how the abundance and function of PHF8 are regulated. Here, we report that PHF8 physically associates with the deubiquitinase USP7. S...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Clin Invest
Main Authors: Wang, Qian, Ma, Shuai, Song, Nan, Li, Xin, Liu, Ling, Yang, Shangda, Ding, Xiang, Shan, Lin, Zhou, Xing, Su, Dongxue, Wang, Yue, Zhang, Qi, Liu, Xinhua, Yu, Na, Zhang, Kai, Shang, Yongfeng, Yao, Zhi, Shi, Lei
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2016
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887182/
https://ncbi.nlm.nih.gov/pubmed/27183383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85747
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