Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis

The histone demethylase PHF8 has been implicated in multiple pathological disorders, including X-linked mental retardation and tumorigenesis. However, it is not clear how the abundance and function of PHF8 are regulated. Here, we report that PHF8 physically associates with the deubiquitinase USP7. S...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Wang, Qian, Ma, Shuai, Song, Nan, Li, Xin, Liu, Ling, Yang, Shangda, Ding, Xiang, Shan, Lin, Zhou, Xing, Su, Dongxue, Wang, Yue, Zhang, Qi, Liu, Xinhua, Yu, Na, Zhang, Kai, Shang, Yongfeng, Yao, Zhi, Shi, Lei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2016
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887182/
https://ncbi.nlm.nih.gov/pubmed/27183383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85747
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items