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USP9X regulates centrosome duplication and promotes breast carcinogenesis

Defective centrosome duplication is implicated in microcephaly and primordial dwarfism as well as various ciliopathies and cancers. Yet, how the centrosome biogenesis is regulated remains poorly understood. Here we report that the X-linked deubiquitinase USP9X is physically associated with centriola...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Li, Xin, Song, Nan, Liu, Ling, Liu, Xinhua, Ding, Xiang, Song, Xin, Yang, Shangda, Shan, Lin, Zhou, Xing, Su, Dongxue, Wang, Yue, Zhang, Qi, Cao, Cheng, Ma, Shuai, Yu, Na, Yang, Fuquan, Wang, Yan, Yao, Zhi, Shang, Yongfeng, Shi, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380967/
https://ncbi.nlm.nih.gov/pubmed/28361952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14866
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