Ubiquitin-specific protease 7 sustains DNA damage response and promotes cervical carcinogenesis

Central to the recognition, signaling, and repair of DNA double-strand breaks (DSBs) are the MRE11-RAD50-NBS1 (MRN) complex and mediator of DNA damage checkpoint protein 1 (MDC1), the interplay of which is essential for initiation and amplification of the DNA damage response (DDR). The intrinsic rul...

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Gepubliceerd in:J Clin Invest
Hoofdauteurs: Su, Dongxue, Ma, Shuai, Shan, Lin, Wang, Yue, Wang, Yuejiao, Cao, Cheng, Liu, Beibei, Yang, Chao, Wang, Liyong, Tian, Shanshan, Ding, Xiang, Liu, Xinhua, Yu, Na, Song, Nan, Liu, Ling, Yang, Shangda, Zhang, Qi, Yang, Fuquan, Zhang, Kai, Shi, Lei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159995/
https://ncbi.nlm.nih.gov/pubmed/30179224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120518
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