A Novel Mouse Model of Autoimmune Thyroiditis Induced by Immunization with Adenovirus Containing Full-Length Thyroglobulin cDNA: Implications to Genetic Studies of Thyroid Autoimmunity

Background: Thyroglobulin (TG) is a key autoantigen in autoimmune thyroid diseases (AITD). Several single nucleotide polymorphisms (SNPs) in the TG locus were shown to be strongly associated with disease susceptibility in both humans and mice, and autoimmune response to TG is the earliest event in t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Thyroid
Prif Awduron: Faustino, Larissa C., Li, Cheuk W., Stefan-Lifshitz, Mihaela, Kim, Kookjoo, Clarke, Oliver B., Tomer, Yaron
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc., publishers 2020
Pynciau:
Immunology, Autoimmunity, and Graves' Ophthalmopathy
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482114/
https://ncbi.nlm.nih.gov/pubmed/32228171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0711
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