A Novel Mouse Model of Autoimmune Thyroiditis Induced by Immunization with Adenovirus Containing Full-Length Thyroglobulin cDNA: Implications to Genetic Studies of Thyroid Autoimmunity

Background: Thyroglobulin (TG) is a key autoantigen in autoimmune thyroid diseases (AITD). Several single nucleotide polymorphisms (SNPs) in the TG locus were shown to be strongly associated with disease susceptibility in both humans and mice, and autoimmune response to TG is the earliest event in t...

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Bibliografske podrobnosti
izdano v:Thyroid
Main Authors: Faustino, Larissa C., Li, Cheuk W., Stefan-Lifshitz, Mihaela, Kim, Kookjoo, Clarke, Oliver B., Tomer, Yaron
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc., publishers 2020
Teme:
Immunology, Autoimmunity, and Graves' Ophthalmopathy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482114/
https://ncbi.nlm.nih.gov/pubmed/32228171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0711
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