A Novel Mouse Model of Autoimmune Thyroiditis Induced by Immunization with Adenovirus Containing Full-Length Thyroglobulin cDNA: Implications to Genetic Studies of Thyroid Autoimmunity

Background: Thyroglobulin (TG) is a key autoantigen in autoimmune thyroid diseases (AITD). Several single nucleotide polymorphisms (SNPs) in the TG locus were shown to be strongly associated with disease susceptibility in both humans and mice, and autoimmune response to TG is the earliest event in t...

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Dettagli Bibliografici
Pubblicato in:Thyroid
Autori principali: Faustino, Larissa C., Li, Cheuk W., Stefan-Lifshitz, Mihaela, Kim, Kookjoo, Clarke, Oliver B., Tomer, Yaron
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2020
Soggetti:
Immunology, Autoimmunity, and Graves' Ophthalmopathy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482114/
https://ncbi.nlm.nih.gov/pubmed/32228171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0711
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