A Novel Mouse Model of Autoimmune Thyroiditis Induced by Immunization with Adenovirus Containing Full-Length Thyroglobulin cDNA: Implications to Genetic Studies of Thyroid Autoimmunity

Background: Thyroglobulin (TG) is a key autoantigen in autoimmune thyroid diseases (AITD). Several single nucleotide polymorphisms (SNPs) in the TG locus were shown to be strongly associated with disease susceptibility in both humans and mice, and autoimmune response to TG is the earliest event in t...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Faustino, Larissa C., Li, Cheuk W., Stefan-Lifshitz, Mihaela, Kim, Kookjoo, Clarke, Oliver B., Tomer, Yaron
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Immunology, Autoimmunity, and Graves' Ophthalmopathy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482114/
https://ncbi.nlm.nih.gov/pubmed/32228171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0711
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