Bruton’s Tyrosine Kinase (BTK) Inhibitor RN486 Overcomes ABCB1-Mediated Multidrug Resistance in Cancer Cells

Overexpression of ATP-binding cassette subfamily B member 1 (ABCB1) remains one of the most vital factors leading to multidrug resistance (MDR). It is important to enhance the effect and bioavailability of chemotherapeutic drugs that are substrates of ABCB1 transporter in ABCB1-overexpression cancer...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Front Cell Dev Biol
Auteurs principaux: Dong, Xing-Duo, Zhang, Meng, Ma, Xiubin, Wang, Jing-Quan, Lei, Zi-Ning, Teng, Qiu-Xu, Li, Yi-Dong, Lin, Lusheng, Feng, Weiguo, Chen, Zhe-Sheng
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Cell and Developmental Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481333/
https://ncbi.nlm.nih.gov/pubmed/32984343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00865
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires