Up-Regulation of RIP3 Alleviates Prostate Cancer Progression by Activation of RIP3/MLKL Signaling Pathway and Induction of Necroptosis

BACKGROUND: The receptor-interacting protein kinase 3 (RIP3/RIPK3) was recently found to be a critical regulator of programmed necrosis/necroptosis. However, the biological role and clinical significance of RIP3 in prostate cancer remain obscure. METHODS: Western blotting and QRT-PCR were performed...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Wang, Ke-jie, Wang, Kai-yun, Zhang, Hui-zhi, Meng, Xiang-yu, Chen, Jun-feng, Wang, Ping, Jiang, Jun-hui, Ma, Qi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480187/
https://ncbi.nlm.nih.gov/pubmed/32984054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01720
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