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Integrin VLA-4 as a PET imaging biomarker of hyper-adhesion in transgenic sickle mice
In sickle cell disease (SCD), very late antigen-4 (VLA-4 or integrin α(4)β(1)) mediates the adhesion of reticulocytes to inflamed, proinflammatory endothelium, a key process in promoting vaso-occlusive episodes (VOEs). We hypothesized that a radionuclide tracer targeting VLA-4 could be harnessed as...
שמור ב:
| הוצא לאור ב: | Blood Adv |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7479956/ https://ncbi.nlm.nih.gov/pubmed/32882004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002642 |
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