Targeted Informatics for Optimal Detection, Characterization, and Quantification of FLT3 Internal Tandem Duplications Across Multiple Next-Generation Sequencing Platforms

Assessment of internal tandem duplications in FLT3 (FLT3-ITDs) and their allelic ratio (AR) is recommended by clinical guidelines for diagnostic workup of acute myeloid leukemia and traditionally performed through capillary electrophoresis (CE). Although significant progress has been made integratin...

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Detalhes bibliográficos
Publicado no:J Mol Diagn
Main Authors: Tsai, Harrison K., Brackett, Diane G., Szeto, David, Frazier, Ryan, MacLeay, Allison, Davineni, Phani, Manning, Danielle K., Garcia, Elizabeth, Lindeman, Neal I., Le, Long P., Lennerz, Jochen K., Gibson, Christopher J., Lindsley, R. Coleman, Kim, Annette S., Nardi, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2020
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479488/
https://ncbi.nlm.nih.gov/pubmed/32603763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2020.06.006
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