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Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines

Chiral 1,2-diamines serve as not only common structure units in bioactive molecules but also useful ligands for a range of catalytic asymmetric reactions. Here, we report a method to access anti-1,2-diamine derivatives. By means of the electron-withdrawing nature of 2- or 4-nitro-phenyl group, a cop...

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Vydáno v:Nat Commun
Hlavní autoři: Gan, Xu-Cheng, Zhang, Cheng-Yuan, Zhong, Feng, Tian, Ping, Yin, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479099/
https://ncbi.nlm.nih.gov/pubmed/32901034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18235-9
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