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Synthesis of cyclic chiral α-amino boronates by copper-catalyzed asymmetric dearomative borylation of indoles

A copper(i)-catalyzed dearomative borylation of N-alkoxycarbonyl protected indole-3-carboxylates has been developed. The boron addition in this reaction occurred regioselectively at the 2-position of indoles followed by diastereoselective protonation, affording the corresponding stable cyclic chiral...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Chen, Lili, Shen, Jun-Jian, Gao, Qian, Xu, Senmiao
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050576/
https://ncbi.nlm.nih.gov/pubmed/30079199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01815d
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