ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation

A human cell contains hundreds to thousands of mitochondrial DNA (mtDNA) packaged into nucleoids. Currently, the segregation and allocation of nucleoids are thought to be passively determined by mitochondrial fusion and division. Here we provide evidence, using live-cell super-resolution imaging, th...

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發表在:Nat Commun
Main Authors: Qin, Jinshan, Guo, Yuting, Xue, Boxin, Shi, Peng, Chen, Yang, Su, Qian Peter, Hao, Huiwen, Zhao, Shujuan, Wu, Congying, Yu, Li, Li, Dong, Sun, Yujie
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478960/
https://ncbi.nlm.nih.gov/pubmed/32901010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18202-4
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