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007 (x2)-3-3: 14-3-3 targeted compounds as double agents
14-3-3 proteins enact a wide range of cellular functions through protein-protein interactions with client proteins. Kaplan and colleagues [1] recently demonstrated that a semi-synthetic compound was able to selectively stabilize or disrupt specific interactions, depending on the binding partner. Thi...
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| Publicado en: | Trends Pharmacol Sci |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7478911/ https://ncbi.nlm.nih.gov/pubmed/32402470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2020.05.001 |
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