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007 (x2)-3-3: 14-3-3 targeted compounds as double agents

14-3-3 proteins enact a wide range of cellular functions through protein-protein interactions with client proteins. Kaplan and colleagues [1] recently demonstrated that a semi-synthetic compound was able to selectively stabilize or disrupt specific interactions, depending on the binding partner. Thi...

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Detalhes bibliográficos
Publicado no:Trends Pharmacol Sci
Main Authors: Gannon, Mary, Yacoubian, Talene
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478911/
https://ncbi.nlm.nih.gov/pubmed/32402470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2020.05.001
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