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IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors

An important comorbidity of chronic inflammation is anemia, which may be related to dysregulated activity of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow (BM). Among HSPCs, we found that the receptor for IL-33, ST2, is expressed preferentially and highly on erythroid progenitor...

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Podrobná bibliografie
Vydáno v:J Exp Med
Hlavní autoři: Swann, James W., Koneva, Lada A., Regan-Komito, Daniel, Sansom, Stephen N., Powrie, Fiona, Griseri, Thibault
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478740/
https://ncbi.nlm.nih.gov/pubmed/32520308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200164
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