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IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors

An important comorbidity of chronic inflammation is anemia, which may be related to dysregulated activity of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow (BM). Among HSPCs, we found that the receptor for IL-33, ST2, is expressed preferentially and highly on erythroid progenitor...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Swann, James W., Koneva, Lada A., Regan-Komito, Daniel, Sansom, Stephen N., Powrie, Fiona, Griseri, Thibault
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478740/
https://ncbi.nlm.nih.gov/pubmed/32520308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200164
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