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Dysregulated Hematopoietic Stem and Progenitor Cell Activity Promotes Interleukin-23-Driven Chronic Intestinal Inflammation

In interleukin-23 (IL-23)-dependent colitis, there is excessive accumulation of short-lived neutrophils and inflammatory monocytes in the intestine. It is unknown whether this reflects changes in mature cell populations or whether the IL-23-driven colitogenic T cell program regulates upstream hemato...

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Detalhes bibliográficos
Main Authors: Griseri, Thibault, McKenzie, Brent S., Schiering, Chris, Powrie, Fiona
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664922/
https://ncbi.nlm.nih.gov/pubmed/23200826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.08.025
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