Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis

The role of intestinal eosinophils in immune homeostasis is enigmatic and the molecular signals that drive them from protective to tissue damaging are unknown. Most commonly associated with Th2 cell-mediated diseases, we describe a role for eosinophils as crucial effectors of the interleukin-23 (IL-...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Griseri, Thibault, Arnold, Isabelle C., Pearson, Claire, Krausgruber, Thomas, Schiering, Chris, Franchini, Fanny, Schulthess, Julie, McKenzie, Brent S., Crocker, Paul R., Powrie, Fiona
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518500/
https://ncbi.nlm.nih.gov/pubmed/26200014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.07.008
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