The Alarmin IL-33 Promotes Regulatory T Cell Function in the Intestine

Foxp3(+) regulatory T cells are abundant in the intestine where they prevent dysregulated inflammatory responses to self and environmental stimuli. It is now appreciated that T(reg) cells acquire tissue-specific adaptations that facilitate their survival and function(1); however, key host factors co...

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Udgivet i:Nature
Main Authors: Schiering, Chris, Krausgruber, Thomas, Chomka, Agnieszka, Fröhlich, Anja, Adelmann, Krista, Wohlfert, Elizabeth A., Pott, Johanna, Griseri, Thibault, Bollrath, Julia, Hegazy, Ahmed N., Harrison, Oliver J., Owens, Benjamin M.J., Löhning, Max, Belkaid, Yasmine, Fallon, Padraic G., Powrie, Fiona
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339042/
https://ncbi.nlm.nih.gov/pubmed/25043027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13577
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