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Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing

Antigen uptake and presentation by naive and germinal center (GC) B cells are different, with the former expressing even low-affinity BCRs efficiently capture and present sufficient antigen to T cells, whereas the latter do so more efficiently after acquiring high-affinity BCRs. We show here that an...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Li, Xin, Gong, Liying, Meli, Alexandre P., Karo-Atar, Danielle, Sun, Weili, Zou, Yongrui, King, Irah L., Gu, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478728/
https://ncbi.nlm.nih.gov/pubmed/32584413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191537
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