PRMT5 is essential for B cell development and germinal center dynamics

Mechanisms regulating B cell development, activation, education in the germinal center (GC) and differentiation, underpin the humoral immune response. Protein arginine methyltransferase 5 (Prmt5), which catalyzes most symmetric dimethyl arginine protein modifications, is overexpressed in B cell lymp...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Litzler, Ludivine C., Zahn, Astrid, Meli, Alexandre P., Hébert, Steven, Patenaude, Anne-Marie, Methot, Stephen P., Sprumont, Adrien, Bois, Thérence, Kitamura, Daisuke, Costantino, Santiago, King, Irah L., Kleinman, Claudia L., Richard, Stéphane, Di Noia, Javier M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318318/
https://ncbi.nlm.nih.gov/pubmed/30604754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07884-6
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