Pharmacological manipulation of AID

Por Methot, Stephen P., Di Noia, Javier M.
Publicado no Oncotarget (2015)

Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1

Por Orthwein, Alexandre, Zahn, Astrid, Methot, Stephen P, Godin, David, Conticello, Silvestro G, Terada, Kazutoyo, Di Noia, Javier M
Publicado em 2012

Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm

Por Methot, Stephen P., Litzler, Ludivine C., Trajtenberg, Felipe, Zahn, Astrid, Robert, Francis, Pelletier, Jerry, Buschiazzo, Alejandro, Magor, Brad G., Di Noia, Javier M.
Publicado no J Exp Med (2015)

Targeting the Tumour Vasculature: Exploitation of Low Oxygenation and Sensitivity to NOS Inhibition by Treatment with a Hypoxic Cytotoxin

Por Baker, Jennifer H. E., Kyle, Alastair H., Bartels, Kirsten L., Methot, Stephen P., Flanagan, Erin J., Balbirnie, Andrew, Cran, Jordan D., Minchinton, Andrew I.
Publicado em 2013

Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination

Por Zahn, Astrid, Eranki, Anil K., Patenaude, Anne-Marie, Methot, Stephen P., Fifield, Heather, Cortizas, Elena M., Foster, Paul, Imai, Kohsuke, Durandy, Anne, Larijani, Mani, Verdun, Ramiro E., Di Noia, Javier M.
Publicado em 2014

A licensing step links AID to transcription elongation for mutagenesis in B cells

Por Methot, Stephen P., Litzler, Ludivine C., Subramani, Poorani Ganesh, Eranki, Anil K., Fifield, Heather, Patenaude, Anne-Marie, Gilmore, Julian C., Santiago, Gabriel E., Bagci, Halil, Côté, Jean-François, Larijani, Mani, Verdun, Ramiro E., Di Noia, Javier M.
Publicado no Nat Commun (2018)