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The Necessity of Using Changes in Absorption Time to Implicate Intestinal Transporter Involvement in Oral Drug-Drug Interactions
INTRODUCTION: In drug discovery and development, it is of high interest to characterize the potential for intestinal drug-drug interactions to alter bioavailability of a victim drug. For drugs that are substrates of both intestinal transporters and enzymes, estimating the relative contribution of ea...
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| Veröffentlicht in: | AAPS J |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7478332/ https://ncbi.nlm.nih.gov/pubmed/32808084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-020-00469-6 |
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