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The Effects of APOE4 on Mitochondrial Dynamics and Proteins in vivo

This study examined the effects of apolipoprotein E4 (APOE4), the most prevalent genetic risk factor for Alzheimer’s disease (AD), on proteins involved in mitochondrial dynamics and autophagy, in the hippocampus of targeted replacement mice. Immunohistochemical measurements revealed that the levels...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Simonovitch, Shira, Schmukler, Eran, Masliah, Eliezer, Pinkas-Kramarski, Ronit, Michaelson, Daniel M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478177/
https://ncbi.nlm.nih.gov/pubmed/31306119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190074
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