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Altered mitochondrial dynamics and function in APOE4-expressing astrocytes
APOE4 is a major risk factor for sporadic Alzheimer’s disease; however, it is unclear how it exerts its pathological effects. Others and we have previously shown that autophagy is impaired in APOE4 compared to APOE3 astrocytes, and demonstrated differences in the expression of mitochondrial dynamics...
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| Publicado en: | Cell Death Dis |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7382473/ https://ncbi.nlm.nih.gov/pubmed/32709881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02776-4 |
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