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The Effects of APOE4 on Mitochondrial Dynamics and Proteins in vivo

This study examined the effects of apolipoprotein E4 (APOE4), the most prevalent genetic risk factor for Alzheimer’s disease (AD), on proteins involved in mitochondrial dynamics and autophagy, in the hippocampus of targeted replacement mice. Immunohistochemical measurements revealed that the levels...

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Dettagli Bibliografici
Pubblicato in:J Alzheimers Dis
Autori principali: Simonovitch, Shira, Schmukler, Eran, Masliah, Eliezer, Pinkas-Kramarski, Ronit, Michaelson, Daniel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478177/
https://ncbi.nlm.nih.gov/pubmed/31306119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190074
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