Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources

BACKGROUND: Adoptive cell therapy with chimeric antigen receptor T cells (CAR-T) has become a standard treatment for patients with certain aggressive B cell malignancies and holds promise to improve the care of patients suffering from numerous other cancers in the future. However, the high manufactu...

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Détails bibliographiques
Publié dans:J Immunother Cancer
Auteurs principaux: Schmidts, Andrea, Marsh, Leah C, Srivastava, Ambike A, Bouffard, Amanda A, Boroughs, Angela C, Scarfò, Irene, Larson, Rebecca C, Bedoya, Felipe, Choi, Bryan D, Frigault, Matthew J, Bailey, Stefanie R, Leick, Mark B, Vatsa, Sonika, Kann, Michael C, Prew, Michelle S, Kleinstiver, Benjamin P, Joung, J Keith, Maus, Marcela V
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2020
Sujets:
Immune Cell Therapies and Immune Cell Engineering
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477986/
https://ncbi.nlm.nih.gov/pubmed/32900862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000990
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