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Dynamic Profiling of Antitumor Activity of CAR T Cells Using Micropatterned Tumor Arrays

Cancer immunotherapy based on the engineering of chimeric antigen receptors (CAR) on T cells has emerged as one of the most promising new therapies for patients with B‐cell malignancies. Preclinical assessments of essential CAR T cell functions such as trafficking and cytotoxicity are critical for a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Adv Sci (Weinh)
Hauptverfasser: Wang, Xiao, Scarfò, Irene, Schmidts, Andrea, Toner, Mehmet, Maus, Marcela V., Irimia, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891905/
https://ncbi.nlm.nih.gov/pubmed/31832320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201901829
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