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Structure-activity relationships of butyrophilin 3 ligands
Phosphoantigens (pAgs) are small phosphorus-containing molecules that stimulate Vγ9Vδ2 T cells with sub-nanomolar cellular potency. Recent work has revealed these compounds work through binding to the transmembrane immunoglobulin butyrophilin 3A1 (BTN3A1) within its intracellular B30.2 domain. Engag...
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| Publicado no: | ChemMedChem |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7477806/ https://ncbi.nlm.nih.gov/pubmed/32453919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000198 |
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