Regioselective functionalization of aryl azoles as powerful tool for the synthesis of pharmaceutically relevant targets

Aryl azole scaffolds are present in a wide range of pharmaceutically relevant molecules. Their ortho-selective metalation at the aryl ring is challenging, due to the competitive metalation of the more acidic heterocycle. Seeking a practical access to a key Active Pharmaceutical Ingredient (API) inte...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Autores principales: Lutter, Ferdinand H., Grokenberger, Lucie, Perego, Luca Alessandro, Broggini, Diego, Lemaire, Sébastien, Wagschal, Simon, Knochel, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477575/
https://ncbi.nlm.nih.gov/pubmed/32895371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18188-z
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares