Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast

Terminal duct lobular units (TDLUs) are the predominant anatomical structures where breast cancers originate. Having lesser degrees of age-related TDLU involution, measured as higher TDLUs counts or more epithelial TDLU substructures (acini), is related to increased breast cancer risk among women wi...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:NPJ Breast Cancer
Main Authors: Bodelon, Clara, Oh, Hannah, Derkach, Andriy, Sampson, Joshua N., Sprague, Brian L., Vacek, Pamela, Weaver, Donald L., Fan, Shaoqi, Palakal, Maya, Papathomas, Daphne, Xiang, Jackie, Patel, Deesha A., Linville, Laura, Clare, Susan E., Visscher, Daniel W., Mies, Carolyn, Hewitt, Stephen M., Brinton, Louise A., Storniolo, Anna Maria V., He, Chunyan, Chanock, Stephen J., Garcia-Closas, Montserrat, Gierach, Gretchen L., Figueroa, Jonine D.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2020
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477555/
https://ncbi.nlm.nih.gov/pubmed/32964115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-020-00184-7
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