Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast

Terminal duct lobular units (TDLUs) are the predominant anatomical structures where breast cancers originate. Having lesser degrees of age-related TDLU involution, measured as higher TDLUs counts or more epithelial TDLU substructures (acini), is related to increased breast cancer risk among women wi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:NPJ Breast Cancer
Prif Awduron: Bodelon, Clara, Oh, Hannah, Derkach, Andriy, Sampson, Joshua N., Sprague, Brian L., Vacek, Pamela, Weaver, Donald L., Fan, Shaoqi, Palakal, Maya, Papathomas, Daphne, Xiang, Jackie, Patel, Deesha A., Linville, Laura, Clare, Susan E., Visscher, Daniel W., Mies, Carolyn, Hewitt, Stephen M., Brinton, Louise A., Storniolo, Anna Maria V., He, Chunyan, Chanock, Stephen J., Garcia-Closas, Montserrat, Gierach, Gretchen L., Figueroa, Jonine D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477555/
https://ncbi.nlm.nih.gov/pubmed/32964115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-020-00184-7
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