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Activation of AMPK by Telmisartan Decreases Basal and PDGF-stimulated VSMC Proliferation via Inhibiting the mTOR/p70S6K Signaling Axis

BACKGROUND: Telmisartan, an angiotensin II type 1 receptor blocker (ARB), is widely used to treat hypertension by blocking the renin-angiotensin-aldosterone system. Although abnormal proliferation of vascular smooth muscle cells (VSMCs) is a well-established contributor to the development of various...

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Bibliografiske detaljer
Udgivet i:J Korean Med Sci
Main Authors: Hwang, Yun-Jin, Park, Jung-Hyun, Cho, Du-Hyong
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Academy of Medical Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476795/
https://ncbi.nlm.nih.gov/pubmed/32893519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2020.35.e289
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