Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade

Phenotypic switch of vascular smooth muscle cells (VSMCs) is characterized by increased expressions of VSMC synthetic markers and decreased levels of VSMC contractile markers, which is an important step for VSMC proliferation and migration during the development and progression of cardiovascular dis...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Lu, Qing-Bo, Wan, Ming-Yu, Wang, Pei-Yao, Zhang, Chen-Xing, Xu, Dong-Yan, Liao, Xiang, Sun, Hai-Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716955/
https://ncbi.nlm.nih.gov/pubmed/29175753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.11.012
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